Cefiderocol MIC quality control ranges in iron-depleted cation-adjusted Mueller-Hinton broth using a CLSI M23-A4 multi-laboratory study design

Cefiderocol (formerly S-649266) is a new catechol-substituted parenteral siderophore cephalosporin with potent in vitro antibacterial activity against Gram-negative isolates including multidrug-resistant strains. A recent study following CLSI M23-A4 quality control guidelines established cefiderocol MIC QC ranges against Escherichia coil ATCC 25922 (0.06-0.5 mu g/mL) and Pseudomonas aeruginosa ATCC 27853 (0.06-0.5 mu g/mL). (C) 2017 Elsevier Inc. All rights reserved.