4.7 Article

Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Medicine, Research & Experimental

Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies

Mihalis S. Kariolis et al.

JOURNAL OF CLINICAL INVESTIGATION (2017)

Article Chemistry, Medicinal

AXL Inhibitors in Cancer: A Medicinal Chemistry Perspective

Samuel H. Myers et al.

JOURNAL OF MEDICINAL CHEMISTRY (2016)

Review Oncology

The influence of subclonal resistance mutations on targeted cancer therapy

Michael W. Schmitt et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2016)

Article Cell Biology

Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase

Stanley G. Kimani et al.

CELL COMMUNICATION AND SIGNALING (2016)

Review Biochemistry & Molecular Biology

Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer

R. B. Birge et al.

CELL DEATH AND DIFFERENTIATION (2016)

Editorial Material Biochemistry & Molecular Biology

Efferocytosis

Sushil Kumar et al.

CURRENT BIOLOGY (2016)

Review Immunology

TAM Receptor Signaling in Immune Homeostasis

Carla V. Rothlin et al.

ANNUAL REVIEW OF IMMUNOLOGY VOL 33 (2015)

Article Oncology

AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma

Toni M. Brand et al.

CLINICAL CANCER RESEARCH (2015)

Article Oncology

AXL as a modulator of sunitinib response in glioblastoma cell lines

Olga Martinho et al.

EXPERIMENTAL CELL RESEARCH (2015)

Article Biochemistry & Molecular Biology

Avalanche for shape and feature-based virtual screening with 3D alignment

David J. Diller et al.

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2015)

Article Virology

Biology of Zika Virus Infection in Human Skin Cells

Rodolphe Hamel et al.

JOURNAL OF VIROLOGY (2015)

Article Oncology

AXL Mediates Resistance to Cetuximab Therapy

Toni M. Brand et al.

CANCER RESEARCH (2014)

Article Biochemistry & Molecular Biology

Overexpression of MERTK Receptor Tyrosine Kinase in Epithelial Cancer Cells Drives Efferocytosis in a Gain-of-Function Capacity

Khanh-Quynh N. Nguyen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Multidisciplinary Sciences

The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells

Magdalena Paolino et al.

NATURE (2014)

Article Biochemistry & Molecular Biology

An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis

Mihalis S. Kariolis et al.

NATURE CHEMICAL BIOLOGY (2014)

Article Immunology

Diversification of TAM receptor tyrosine kinase function

Anna Zagorska et al.

NATURE IMMUNOLOGY (2014)

Article Multidisciplinary Sciences

Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET

Erinn B. Rankin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Immunology

Contribution of defective PS recognition and efferocytosis to chronic inflammation and autoimmunity

Stanley Gititu Kimani et al.

FRONTIERS IN IMMUNOLOGY (2014)

Article Medicine, Research & Experimental

MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis

Rebecca S. Cook et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Medicine, Research & Experimental

MERTK receptor tyrosine kinase is a therapeutic target in melanoma

Jennifer Schlegel et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Oncology

Emerging Paradigms in the Development of Resistance to Tyrosine Kinase Inhibitors in Lung Cancer

Justin F. Gainor et al.

JOURNAL OF CLINICAL ONCOLOGY (2013)

Article Microbiology

The TIM and TAM Families of Phosphatidylserine Receptors Mediate Dengue Virus Entry

Laurent Meertens et al.

CELL HOST & MICROBE (2012)

Article Chemistry, Medicinal

ZINC: A Free Tool to Discover Chemistry for Biology

John J. Irwin et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2012)

Article Genetics & Heredity

Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer

Zhenfeng Zhang et al.

NATURE GENETICS (2012)

Article Cardiac & Cardiovascular Systems

Elevated plasma gas6 levels are associated with venous thromboembolic disease

Mark D. Blostein et al.

JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2011)

Review Oncology

Targeting Axl and Mer Kinases in Cancer

Anupam Verma et al.

MOLECULAR CANCER THERAPEUTICS (2011)

Article Chemistry, Medicinal

Identifying and Characterizing Binding Sites and Assessing Druggability

Thomas A. Halgren

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2009)

Article Biochemistry & Molecular Biology

TAM receptors are pleiotropic inhibitors of the innate immune response

Carla V. Rothlin et al.

Article Hematology

Role of the growth arrest-specific gene 6 (gas6) product in thrombus stabilization

Francois Saller et al.

BLOOD CELLS MOLECULES AND DISEASES (2006)

Article Biochemistry & Molecular Biology

Structural basis for Gas6-Axl signalling

T Sasaki et al.

EMBO JOURNAL (2006)

Article Biochemical Research Methods

Q-SiteFinder: an energy-based method for the prediction of protein-ligand binding sites

ATR Laurie et al.

BIOINFORMATICS (2005)

Article Hematology

Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses

WR Gould et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2005)

Article Chemistry, Medicinal

ZINC - A free database of commercially available compounds for virtual screening

JJ Irwin et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2005)

Article Immunology

Phosphatidylserine on HIV envelope is a cofactor for infection of monocytic cells

MK Callahan et al.

JOURNAL OF IMMUNOLOGY (2003)