4.7 Article

Comparative analysis of image classification methods for automatic diagnosis of ophthalmic images

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SCIENTIFIC REPORTS
卷 7, 期 -, 页码 -

出版社

NATURE PORTFOLIO
DOI: 10.1038/srep41545

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资金

  1. NSFC [91546101, 11401454]
  2. Guangdong Provincial Natural Science Foundation [YQ2015006, 2014A030306030, 2014TQ01R573, 2013B020400003]
  3. New Star of Pearl River Science and Technology of Guangzhou City [2014J2200060]
  4. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University [2015ykzd11, 2015QN01]
  5. Special Program for Applied Research on Super Computation of the NSFC-Guangdong Joint Fund
  6. Clinical Research and Translational Medical Center for Pediatric Cataract in Guangzhou City
  7. Fundamental Research Funds for the Central Universities [BDZ011401, JB151005]
  8. Novel Technology Research of Universities Cooperation Project
  9. State Key Laboratory of Satellite Navigation System and Equipment Technology [KX152600027]
  10. Pearl River Scholar Program of Guangdong Province

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There are many image classification methods, but it remains unclear which methods are most helpful for analyzing and intelligently identifying ophthalmic images. We select representative slit-lamp images which show the complexity of ocular images as research material to compare image classification algorithms for diagnosing ophthalmic diseases. To facilitate this study, some feature extraction algorithms and classifiers are combined to automatic diagnose pediatric cataract with same dataset and then their performance are compared using multiple criteria. This comparative study reveals the general characteristics of the existing methods for automatic identification of ophthalmic images and provides new insights into the strengths and shortcomings of these methods. The relevant methods (local binary pattern + SVMs, wavelet transformation + SVMs) which achieve an average accuracy of 87% and can be adopted in specific situations to aid doctors in preliminarily disease screening. Furthermore, some methods requiring fewer computational resources and less time could be applied in remote places or mobile devices to assist individuals in understanding the condition of their body. In addition, it would be helpful to accelerate the development of innovative approaches and to apply these methods to assist doctors in diagnosing ophthalmic disease.

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