相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Excitable waves and direction-sensing in Dictyostelium discoideum: steps towards a chemotaxis model
Arpan Bhowmik et al.
PHYSICAL BIOLOGY (2016)
Clustering reveals limits of parameter identifiability in multi-parameter models of biochemical dynamics
Karol Nienaltowski et al.
BMC SYSTEMS BIOLOGY (2015)
Receptor Level Mechanisms Are Required for Epidermal Growth Factor (EGF)-stimulated Extracellular Signal-regulated Kinase (ERK) Activity Pulses
Breanne Sparta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Frequency modulation of ERK activation dynamics rewires cell fate
Hyunryul Ryu et al.
MOLECULAR SYSTEMS BIOLOGY (2015)
Orthogonal control of expression mean and variance by epigenetic features at different genomic loci
Siddharth S. Dey et al.
MOLECULAR SYSTEMS BIOLOGY (2015)
ERK reinforces actin polymerization to power persistent edge protrusion during motility
Michelle C. Mendoza et al.
SCIENCE SIGNALING (2015)
Digital signaling decouples activation probability and population heterogeneity
Ryan A. Kellogg et al.
ELIFE (2015)
ERK reinforces actin polymerization to power persistent edge protrusion during motility
Michelle C. Mendoza et al.
SCIENCE SIGNALING (2015)
Computational Analysis of an Autophagy/Translation Switch Based on Mutual Inhibition of MTORC1 and ULK1
Paulina Szymanska et al.
PLOS ONE (2015)
High-Sensitivity Measurements of Multiple Kinase Activities in Live Single Cells
Sergi Regot et al.
CELL (2014)
RAF neighborhood: Protein-protein interaction in the Raf/Mek/Erk pathway
Botond Cseh et al.
FEBS LETTERS (2014)
Protein interaction switches coordinate Raf-1 and MST2/Hippo signalling
David Romano et al.
NATURE CELL BIOLOGY (2014)
Targeting RAS-ERK signalling in cancer: promises and challenges
Ahmed A. Samatar et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
Accurate information transmission through dynamic biochemical signaling networks
Jangir Selimkhanov et al.
SCIENCE (2014)
Frequency-Modulated Pulses of ERK Activity Transmit Quantitative Proliferation Signals
John G. Albeck et al.
MOLECULAR CELL (2013)
Stochastic ERK Activation Induced by Noise and Cell-to-Cell Propagation Regulates Cell Density-Dependent Proliferation
Kazuhiro Aoki et al.
MOLECULAR CELL (2013)
Spontaneous NF-κB Activation by Autocrine TNFα Signaling: A Computational Analysis
Jakub Pekalski et al.
PLOS ONE (2013)
Interaction of Motility, Directional Sensing, and Polarity Modules Recreates the Behaviors of Chemotaxing Cells
Changji Shi et al.
PLOS COMPUTATIONAL BIOLOGY (2013)
ERK1/2 MAP kinases: Structure, function, and regulation
Robert Roskoski
PHARMACOLOGICAL RESEARCH (2012)
Are Biological Systems Poised at Criticality?
Thierry Mora et al.
JOURNAL OF STATISTICAL PHYSICS (2011)
ERK-MAPK Drives Lamellipodia Protrusion by Activating the WAVE2 Regulatory Complex
Michelle C. Mendoza et al.
MOLECULAR CELL (2011)
Feedback regulation of EGFR signalling: decision making by early and delayed loops
Roi Avraham et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
Information Transduction Capacity of Noisy Biochemical Signaling Networks
Raymond Cheong et al.
SCIENCE (2011)
B Cell Activation Triggered by the Formation of the Small Receptor Cluster: A Computational Study
Beata Hat et al.
PLOS COMPUTATIONAL BIOLOGY (2011)
Spatial distribution and dose-response relationship for different operation modes in a reaction-diffusion model of the MAPK cascade
Qi Zhao et al.
PHYSICAL BIOLOGY (2011)
RAF protein-serine/threonine kinases: Structure and regulation
Robert Roskoski
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Systematic Quantification of Negative Feedback Mechanisms in the Extracellular Signal-regulated Kinase (ERK) Signaling Network
Murat Cirit et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Signalling ballet in space and time
Boris N. Kholodenko et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Cells navigate with a local-excitation, global-inhibition-biased excitable network
Yuan Xiong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Digital Signaling and Hysteresis Characterize Ras Activation in Lymphoid Cells
Jayajit Das et al.
CELL (2009)
Spatially distributed cell signalling
Boris N. Kholodenko
FEBS LETTERS (2009)
Exploring mechanisms of oscillations in p53 and nuclear factor-κB systems
B. Hat et al.
IET SYSTEMS BIOLOGY (2009)
Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway
Sung-Young Shin et al.
JOURNAL OF CELL SCIENCE (2009)
Regulation of kinase activity by diffusion and feedback
Bogdan Kazmierczak et al.
JOURNAL OF THEORETICAL BIOLOGY (2009)
Cell fate decisions are specified by the dynamic ERK interactome
Alex von Kriegsheim et al.
NATURE CELL BIOLOGY (2009)
Frustrated bistability as a means to engineer oscillations in biological systems
S. Krishna et al.
PHYSICAL BIOLOGY (2009)
Wave-pinning and cell polarity from a bistable reaction-diffusion system
Yoichiro Mori et al.
BIOPHYSICAL JOURNAL (2008)
Robust single-particle tracking in live-cell time-lapse sequences
Khuloud Jaqaman et al.
NATURE METHODS (2008)
EGF-receptor-mediated mammary epithelial cell migration is driven by sustained ERK signaling from autocrine stimulation
Elizabeth J. Joslin et al.
JOURNAL OF CELL SCIENCE (2007)
Stochastic simulation of chemical kinetics
Daniel T. Gillespie
ANNUAL REVIEW OF PHYSICAL CHEMISTRY (2007)
Stochastic mRNA synthesis in mammalian cells
Arjun Raj et al.
PLOS BIOLOGY (2006)
Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops
Anatoly Kiyatkin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
SUNDIALS: Suite of nonlinear and differential/algebraic equation solvers
AC Hindmarsh et al.
ACM TRANSACTIONS ON MATHEMATICAL SOFTWARE (2005)
Raf-1 regulates Rho signaling and cell migration
K Ehrenreiter et al.
JOURNAL OF CELL BIOLOGY (2005)
Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades
NI Markevich et al.
JOURNAL OF CELL BIOLOGY (2004)
Self-organization of polarized cell signaling via autocrine circuits: Computational model analysis
IV Maly et al.
BIOPHYSICAL JOURNAL (2004)
Oscillations in NF-κB signaling control the dynamics of gene expression
DE Nelson et al.
SCIENCE (2004)
Mechanotransduction through growth-factor shedding into the extracellular space
DJ Tschumperlin et al.
NATURE (2004)
A positive-feedback-based bistable 'memory module' that governs a cell fate decision
W Xiong et al.
NATURE (2003)
Local signaling by the EGF receptor
SJ Kempiak et al.
JOURNAL OF CELL BIOLOGY (2003)
Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention
F Chang et al.
LEUKEMIA (2003)
MATCONT: A MATLAB package for numerical bifurcation analysis of ODEs
A Dhooge et al.
ACM TRANSACTIONS ON MATHEMATICAL SOFTWARE (2003)
Auditory sensitivity provided by self-tuned critical oscillations of hair cells
S Camalet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades
BN Kholodenko
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)