相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Proteolysis of α-synuclein fibrils in the lysosomal pathway limits induction of inclusion pathology
Amanda N. Sacino et al.
JOURNAL OF NEUROCHEMISTRY (2017)
Effects of Serine 129 Phosphorylation on α-Synuclein Aggregation, Membrane Association, and Internalization
Filsy Samuel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Immunomodulation as a neuroprotective and therapeutic strategy for Parkinson's disease
Katherine E. Olson et al.
CURRENT OPINION IN PHARMACOLOGY (2016)
α-Synuclein vaccination modulates regulatory T cell activation and microglia in the absence of brain pathology
Josefine R. Christiansen et al.
JOURNAL OF NEUROINFLAMMATION (2016)
New tools for studying microglia in the mouse and human CNS
Mariko L. Bennett et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3
Xiaobo Mao et al.
SCIENCE (2016)
Phosphorylation induces distinct alpha-synuclein strain formation
Meng-Rong Ma et al.
SCIENTIFIC REPORTS (2016)
α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
W. Peelaerts et al.
NATURE (2015)
Ginsenoside Rb1 inhibits fibrillation and toxicity of alpha-synuclein and disaggregates preformed fibrils
Mustafa T. Ardah et al.
NEUROBIOLOGY OF DISEASE (2015)
Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology
Nishant N. Vaikath et al.
NEUROBIOLOGY OF DISEASE (2015)
Progressive Aggregation of Alpha-Synuclein and Selective Degeneration of Lewy Inclusion-Bearing Neurons in a Mouse Model of Parkinsonism
Valerie R. Osterberg et al.
CELL REPORTS (2015)
Myeloid Dendritic Cells are Potential Players in Human Neurodegenerative Diseases
Paola Bossu et al.
FRONTIERS IN IMMUNOLOGY (2015)
Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys
Ariadna Recasens et al.
ANNALS OF NEUROLOGY (2014)
In Vitro Phosphorylation Does not Influence the Aggregation Kinetics of WT α-Synuclein in Contrast to Its Phosphorylation Mutants
Sarah Schreurs et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)
Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases
Jing L. Guo et al.
NATURE MEDICINE (2014)
Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite-like aggregates
Laura A. Volpicelli-Daley et al.
NATURE PROTOCOLS (2014)
Structure activity relationship of phenolic acid inhibitors of α-synuclein fibril formation and toxicity
Mustafa T. Ardah et al.
FRONTIERS IN AGING NEUROSCIENCE (2014)
Protein phosphorylation in neurodegeneration: friend or foe?
Sandra Tenreiro et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2014)
Boosting chaperone-mediated autophagy in vivo mitigates α-synuclein-induced neurodegeneration
Maria Xilouri et al.
BRAIN (2013)
Prion-like spreading of pathological α-synuclein in brain
Masami Masuda-Suzukake et al.
BRAIN (2013)
Ser129D mutant alpha-synuclein induces earlier motor dysfunction while S129A results in distinctive pathology in a rat model of Parkinson's disease
Fabia Febbraro et al.
NEUROBIOLOGY OF DISEASE (2013)
Divergent α-synuclein solubility and aggregation properties in G2019S LRRK2 Parkinson's disease brains with Lewy Body pathology compared to idiopathic cases
Adamantios Mamais et al.
NEUROBIOLOGY OF DISEASE (2013)
The prion hypothesis in Parkinson's disease: Braak to the future
Naomi P Visanji et al.
Acta Neuropathologica Communications (2013)
Phosphorylation of α-Synuclein Protein at Ser-129 Reduces Neuronal Dysfunction by Lowering Its Membrane Binding Property in Caenorhabditis elegans
Tomoki Kuwahara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
Kelvin C. Luk et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Fiji: an open-source platform for biological-image analysis
Johannes Schindelin et al.
NATURE METHODS (2012)
Prion-like acceleration of a synucleinopathy in a transgenic mouse model
Anne-Laure Mougenot et al.
NEUROBIOLOGY OF AGING (2012)
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
Kelvin C. Luk et al.
SCIENCE (2012)
Enhanced Phosphatase Activity Attenuates α-Synucleinopathy in a Mouse Model
Kang-Woo Lee et al.
JOURNAL OF NEUROSCIENCE (2011)
Contribution of Alanine-76 and Serine Phosphorylation in alpha-Synuclein Membrane Association and Aggregation in Yeasts
Michael Fiske et al.
PARKINSONS DISEASE (2011)
Phosphorylation of Synucleins by Members of the Polo-like Kinase Family
Martial K. Mbefo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Prion-like transmission of protein aggregates in neurodegenerative diseases
Patrik Brundin et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Selective noradrenergic vulnerability in alpha-synuclein transgenic mice
Evangelos Sotiriou et al.
NEUROBIOLOGY OF AGING (2010)
Inputs to the dorsal striatum of the mouse reflect the parallel circuit architecture of the forebrain
Weixing X. Pan et al.
FRONTIERS IN NEUROANATOMY (2010)
α-Synuclein Aggregation and Ser-129 Phosphorylation-dependent Cell Death in Oligodendroglial Cells
Christine L. Kragh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of α-synuclein
Katerina E. Paleologou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Dopamine neuron systems in the brain:: an update
Anders Bjorklund et al.
TRENDS IN NEUROSCIENCES (2007)
Phosphorylation of Ser-129 is the dominant pathological modification of α-synuclein in familial and sporadic Lewy body disease
John P. Anderson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
α-Synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y cells
WW Smith et al.
JOURNAL OF NEUROSCIENCE (2005)
α-synuclein locus triplication causes Parkinson's disease
AB Singleton et al.
SCIENCE (2003)
Hyperphosphorylation and insolubility of α-synuclein in transgenic mouse oligodendrocytes
PJ Kahle et al.
EMBO REPORTS (2002)
α-Synuclein is phosphorylated in synucleinopathy lesions
H Fujiwara et al.
NATURE CELL BIOLOGY (2002)