期刊
RSC ADVANCES
卷 7, 期 87, 页码 55288-55295出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7ra10634c
关键词
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资金
- Nano Material Technology Development Program of the Korean National Research Foundation (NRF) - Korean Ministry of Education, Science, and Technology [2012M3A7B4049675]
- Priority Research Centers Program [2014R1A6A1031189]
A novel and facile copper-catalyzed direct coupling for the synthesis of diverse and functionalized 3-indolyl benzoxazin-2-ones from benzoxazin-2-ones and indoles has been developed. This newmethodology offers an easy and rapid approach to a variety of 3-indolylbenzo[b][1,4] oxazin-2-ones in high yield. As an application of this protocol, a gram-scale synthesis of naturally occurring cephalandole A has also been accomplished.
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