期刊
BIOSENSORS & BIOELECTRONICS
卷 92, 期 -, 页码 618-623出版社
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2016.10.047
关键词
Nanosensor; Fluorescence detection; Graphene quantum dots; Metronidazole; Molecularly imprinted polymer; Inorganic silica polymer
类别
资金
- Research Council of University of Tehran [6102027]
A novel optical nanosensor for detection of Metronidazole in biological samples was reported. Graphene quantum dots embedded silica molecular imprinted polymer (GQDs-embedded SMIP) was synthesized and used as a selective fluorescent probe for Metronidazole detection. The new synthesized GQDs-embedded SMIP showed strong fluorescent emission at 450 nm excited at 365 nm which quenched in presence of Metronidazole as a template molecule.. The quenching was proportional to the concentration of Metronidazole in a linear range of at least 0.2 mu M to 15 mu M. The limit of detection for metronidazole determination was obtained 0.15 mu M. The nanosensor successfully worked in plasma matrixes.
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