期刊
RSC ADVANCES
卷 7, 期 53, 页码 33285-33292出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7ra01175j
关键词
-
资金
- National Natural Science Foundation of China [51201056, 81500886]
- Technology Foundation for returned overseas Chinese scholars [C2015003038]
- Natural Science Foundation of Hebei Province of China [E2013202021, E2017202032]
- Outstanding Youth Foundation of Hebei Province of China [E2015202282]
- Tianjin Natural Science Foundation [16JCYBJC28700]
- Science and Technology Correspondent Project of Tianjin [14JCTPJC00496]
A micro-nano structured titanium (Ti) surface consisting of titania (TiO2) and hydroxyapatite (HA) was produced by one-step micro-arc oxidation (MAO) to improve the corrosion resistance and biological properties. The corrosion resistance was evaluated in simulated body fluids (SBF) by electrochemical impedance spectroscopy ( EIS) and anodic polarisation tests. The biological properties were investigated by in vitro cell co-culture experiments and in vivo experiments. The results showed that a microstructured TiO2 coating loaded with a nanostructured HA slice could be obtained on the Ti substrate during the MAO process. The MAO induced composite coating showed an increased resistance value and corrosion potential. It also promoted the cell behaviors (proliferation and spreading) on the Ti surface. After implantation in the rat tibias, the bonding strength between the bone tissues and implant was enhanced. The improved corrosion resistance was attributed to the increased thickness of the oxide layer, and the enhanced biological properties resulted from the micro-nanostructure and HA on the Ti surface. Based on these results, it was concluded that the micro-nano structured Ti surface consisting of TiO2 and HA prepared by MAO has great potential to be applied in the clinic.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据