期刊
ARTIFICIAL ORGANS
卷 41, 期 6, 页码 509-518出版社
WILEY
DOI: 10.1111/aor.12947
关键词
Acid concentrate; Base concentrate; Sodium bicarbonate; Hemodialysis; Three-stream; Dialysis fluid; Delivery system; Acetic acid; Sodium acetate; Sodium diacetate
Hemodialysis patients can acquire buffer base (i.e., bicarbonate and buffer base equivalents of certain organic anions) from the acid and base concentrates of a three-stream, dual-concentrate, bicarbonate-based, dialysis solution delivery machine. The differences between dialysis fluid concentrate systems containing acetic acid versus sodium diacetate in the amount of potential buffering power were reviewed. Any organic anion such as acetate, citrate, or lactate (unless when combined with hydrogen) delivered to the body has the potential of being converted to bicarbonate. The prescribing physician aware of the role that organic anions in the concentrates can play in providing buffering power to the final dialysis fluid, will have a better knowledge of the amount of bicarbonate and bicarbonate precursors delivered to the patient.
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