期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 61, 期 6, 页码 -出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00356-17
关键词
Klebsiella pneumoniae; heteroresistance; colistin; mgrB
Here, we report the description of a colistin-heteroresistant Klebsiella pneumoniae isolate fortuitously isolated from the stool sample of a patient with suspicion of tuberculosis in a public hospital of Marseille, France. In the colistin-resistant subpopulation, a mutation in the mgrB gene leading to a premature stop codon was found, and the hypermucoviscous phenotype was lost. Susceptibility to other antibiotics remained unchanged. To our knowledge, this is the first identification of such a colistin-heteroresistant Klebsiella pneumoniae isolate in France.
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