期刊
AMERICAN JOURNAL OF HYPERTENSION
卷 30, 期 7, 页码 690-699出版社
OXFORD UNIV PRESS
DOI: 10.1093/ajh/hpx034
关键词
blood pressure; blood pressure variability; healthy lifestyle; hypertension; lifestyle-score; population-based
资金
- Liechtenstein Government
- Swiss Heart Foundation
- Swiss Society of Hypertension
- University of Basel
- University Hospital Basel
- Hanela Foundation
- Schiller AG
- Novartis
- Swiss National Science Foundation [PP00P3_133681, PP00P3_159322]
- Swiss National Science Foundation (SNF) [PP00P3_159322] Funding Source: Swiss National Science Foundation (SNF)
BACKGROUND The aim of this study was to assess the relationships between healthy lifestyle metrics and blood pressure variability (BPV) in young and healthy adults. METHODS A population-based sample of 1,999 individuals aged 25-41 years was investigated. A lifestyle-score from 0 (most unhealthy) to 7 (most healthy) was calculated by giving one point for each of the following components: never smoking cigarettes, adhering to a healthy diet, performing moderate or intense physical activity, having a body mass index <25 kg/m(2), a total cholesterol <200 mg/dl, a glycated hemoglobin <5.7%, or a conventional BP <120/80 mm Hg. Standardized ambulatory 24-hour BP measurements were obtained in all individuals. BPV was defined as the SD of all individual ambulatory BP recordings. We constructed multivariable linear regression models to assess the relationships between the lifestyle-score and BPV. None of the results were adjusted for multiple testing. RESULTS Median age was 37 years and 46.8% were men. With increasing lifestyle-score, systolic and diastolic BPV is decreasing linearly (P for trend <0.0001), even after multivariable adjustment. Per 1-point increase in lifestyle-score, the beta-coefficient (95% confidence interval) for systolic and diastolic 24-hour BPV was -0.03 (-0.03; -0.02) and -0.04 (-0.05; -0.03), respectively, both P for trend <0.0001. These relationships were attenuated but remained statistically significant after additional adjustment for mean individual BP. CONCLUSION In this study of young and healthy adults, adopting a healthy lifestyle was associated with a lower BPV. These associations were independent of mean BP levels.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据