期刊
NUTRIENTS
卷 9, 期 4, 页码 -出版社
MDPI
DOI: 10.3390/nu9040420
关键词
food frequency questionnaire; arsenic exposure; pregnancy; Bangladesh; dietary assessment
资金
- USA National Institutes of Health [ES 011622, ES 05947, ES 00002]
- Talent Promotion Project of the Research Center for Environmental Medicine at Kaohsiung Medical University, Taiwan [105KMUOR03]
- NIH [5T32ES007069]
- [K24HD069408]
This prospective study evaluated the relationship between long-term dietary habits and total arsenic (As) concentration in toenail clippings in a cohort of 1616 pregnant women in the Bangladeshi administrative regions of Sirajdikhan and Pabna Sadar. Diet was assessed at GestationWeek 28 and at Postpartum Month 1, using a locally-validated dish-based semi-quantitative food-frequency questionnaire. Toenail As concentration was analyzed by microwave-assisted acid digestion and inductively coupled plasma mass spectrometry. Associations between natural log-transformed consumption of individual food items and temporally matched natural log-transformed toenail As concentration were quantified using general linear models that accounted for As concentration in the primary drinking water source and other potential confounders. The analysis was stratified by As in drinking water (<= 50 mu g/L versus >50 mu g/L) and the time of dietary assessment (GestationWeek 28 versus Postpartum Week 1). Interestingly, toenail As was not significantly associated with consumption of plain rice as hypothesized. However, toenail As was positively associated with consumption of several vegetable, fish and meat items and was negatively associated with consumption of rice, cereal, fruits, and milk based food items. Further studies in pregnant women are needed to compare As metabolism at different levels of As exposure and the interaction between dietary composition and As absorption.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据