期刊
DIGESTIVE DISEASES AND SCIENCES
卷 62, 期 7, 页码 1796-1807出版社
SPRINGER
DOI: 10.1007/s10620-017-4491-4
关键词
Pancreatic cancer; Intraductal papillary mucinous neoplasm; Mucinous cystic neoplasm; Serous cystadenoma
资金
- Pancreatic Cancer Action Network (PanCAN) Translational Research Grant
With increased utilization and ongoing advancements in cross-sectional abdominal imaging, the identification of a pancreatic cyst has become a frequent finding. While many pancreatic cysts are associated with a benign clinical course, others may transform into pancreatic ductal adenocarcinoma. However, distinguishing a benign from a malignant pancreatic cyst or pancreatic cyst with malignant potential on the basis of standard clinical findings, imaging parameters and ancillary studies can be challenging. Hence, a significant interest within the past decade has been the identification of novel biomarkers to accurately classify and prognosticate a pancreatic cyst. Within this review, we discuss novel DNA, miRNA, protein and metabolite biomarkers, and their relevance in clinical practice. In addition, we focus on future areas of research that have the potential to change pancreatic cyst management.
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