期刊
COLLOIDS AND SURFACES B-BIOINTERFACES
卷 155, 期 -, 页码 61-70出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.colsurfb.2017.03.054
关键词
Green synthesis; Silver nanoparticles; Trimethyl chitosan nitrate; Catalytic activity; Antibacterial activity; Multidrug-resistant Acinetobacter baumannii
资金
- Ministry of Science and Technology [MOST 105-2623-E-016-002-D, MOST 105-2623-E-016-001- D]
- National Defense Medical Center of the Republic of China [MAB-105-112, IPM-105-G8]
We report a facile route for the green synthesis of trimethyl chitosan nitrate-capped silver nanopartides (TMCN-AgNPs) with positive surface charge. In this synthesis, silver nitrate, glucose, and trimethyl chitosan nitrate (TMCN) were used as silver precursor, reducing agent, and stabilizer, respectively. The reaction was carried out in a stirred basic aqueous medium at room temperature without the use of energy-consuming or expensive equipment. We investigated the effects of the concentrations of NaOH, glucose, and TMCN on the particle size, zeta potential, and formation yield. The AgNPs were characterized by UV-vis spectroscopy, photon correlation spectroscopy, laser Doppler anemometry, transmission electron microscopy, X-ray diffraction, and X-ray photoelectron spectroscopy. The catalytic activity of the TMCN-AgNPs was studied by the reduction of 4-nitrophenol using NaBH4 as a reducing agent. We evaluated the antibacterial effects of the TMCN-AgNPs on Acinetobacter baumannii, Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus using the broth microdilution method. The results showed that both gram-positive and gram-negative bacteria were killed by the TMCN-AgNPs at very low concentration (<6.13 mu g/mL). Moreover, the TMCN-AgNPs also showed high antibacterial activity against clinically isolated multidrug-resistant A. baumannii strains, and the minimum inhibitory concentration (MIC) was <= 12.25 mu g/mL. (C) 2017 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据