期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 23, 期 35, 页码 8348-8352出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201701446
关键词
amphiphiles; DNA nanostructures; responsive systems; self-assembly; vesicles
资金
- DBT [BT/PR7030/NNT/28/63/2012]
- CSIR
- UGC
A pH-responsive DNAsome derived from the amphiphilicity-driven self-assembly of DNA amphiphile containing C-rich DNA sequence is reported. The acidification of DNAsome induces a structural change of C-rich DNA from random coil to an i-motif structure that triggers the disassembly of DNAsome and its subsequent morphological transformation into an open entangled network. The encapsulation of a hydrophobic guest into the membrane of DNAsome and its pH-triggered release upon acidification of DNAsome is also demonstrated.
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