期刊
ANALYTICAL BIOCHEMISTRY
卷 531, 期 -, 页码 45-47出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ab.2017.05.021
关键词
SPRi; EpCAM; Hybridoma; Antibody/protein excretion; Single cells; SPR cytometry; Microwell; McSPRInter
资金
- NWO [15327]
Here the feasibility is demonstrated that by combining Surface Plasmon Resonance Imaging (SPRi) and self-sorting microwell technology product secretion of individual cells can be monitored. Additionally isolation of the selected cells can be performed by punching the cells from the microwells using coordinates of the positions of microwells obtained with SPRi. Cells of interest can be retrieved sterile from the microwell array for further cultivation. (C) 2017 The Author(s). Published by Elsevier Inc.
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