相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A Genetically Encoded FRET Probe to Detect Intranucleosomal Histone H3K9 or H3K14 Acetylation Using BRD4, a BET Family Member
Shiho Nakaoka et al.
ACS CHEMICAL BIOLOGY (2016)
Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes
Ram Madabhushi et al.
CELL (2015)
Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction
Tomoyoshi Yamano et al.
IMMUNITY (2015)
Dominant Mutations in the Autoimmune Regulator AIRE Are Associated with Common Organ-Specific Autoimmune Diseases
Bergithe E. Oftedal et al.
IMMUNITY (2015)
PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator-dependent autoimmunity
Anne-Laure Mathieu et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2015)
The nuclear pore complex - structure and function at a glance
Greg Kabachinski et al.
JOURNAL OF CELL SCIENCE (2015)
The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance
Anna Chuprin et al.
NATURE IMMUNOLOGY (2015)
Getting up to speed with transcription elongation by RNA polymerase II
Iris Jonkers et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)
Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells
Hideyuki Yoshida et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
The versatile roles of CARDs in regulating apoptosis, inflammation, and NF-κB signaling
Wen-Pin Kao et al.
APOPTOSIS (2015)
Homeodomain-Interacting Protein Kinase 2, a Novel Autoimmune Regulator Interaction Partner, Modulates Promiscuous Gene Expression in Medullary Thymic Epithelial Cells
Kristin Rattay et al.
JOURNAL OF IMMUNOLOGY (2015)
The biophysical and biochemical properties of the autoimmune regulator (AIRE) protein
Roberto Perniola et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)
A requiem to the nuclear matrix: from a controversial concept to 3D organization of the nucleus
S. V. Razin et al.
CHROMOSOMA (2014)
Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia
Stephen N. Sansom et al.
GENOME RESEARCH (2014)
The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance
Michael Waterfield et al.
NATURE IMMUNOLOGY (2014)
BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones
Tomohiko Kanno et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)
An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription
Matthieu Girauda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development
Jennifer E. Cowan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Enhanced Chromatin Dynamics by FACT Promotes Transcriptional Restart after UV-Induced DNA Damage
Christoffel Dinant et al.
MOLECULAR CELL (2013)
Aire's plant homeodomain(PHD)-2 is critical for induction of immunological tolerance
Siyoung Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The PML-Interacting Protein DAXX: Histone Loading Gets into the Picture
Paolo Salomoni
FRONTIERS IN ONCOLOGY (2013)
Autoimmune regulator is acetylated by transcription coactivator CBP/p300
Mario Saare et al.
EXPERIMENTAL CELL RESEARCH (2012)
Unmodified Histone H3K4 and DNA-Dependent Protein Kinase Recruit Autoimmune Regulator to Target Genes
Kristina Zumer et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome
Massimiliano Gaetani et al.
NUCLEIC ACIDS RESEARCH (2012)
Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells
Matthieu Giraud et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Thymic epithelial cells: working class heroes for T cell development and repertoire selection
Graham Anderson et al.
TRENDS IN IMMUNOLOGY (2012)
Estrogen receptor α-mediated transcription induces cell cycle-dependent DNA double-strand breaks
Laura M. Williamson et al.
CARCINOGENESIS (2011)
Aire's Partners in the Molecular Control of Immunological Tolerance
Jakub Abramson et al.
CELL (2010)
Posttranslational modifications of NF-kappa B: Another layer of regulation for NF-kappa B signaling pathway
Bo Huang et al.
CELLULAR SIGNALLING (2010)
Autoimmune Polyendocrine Syndromes: Clues to Type 1 Diabetes Pathogenesis
Eystein S. Husebye et al.
IMMUNITY (2010)
DAXX Is a New AIRE-interacting Protein
Allesandra Meloni et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation
Yumiko Nishikawa et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
A mini review of MAR-binding proteins
Tian-Yun Wang et al.
MOLECULAR BIOLOGY REPORTS (2010)
Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements
Michael C. Haffner et al.
NATURE GENETICS (2010)
A Role of DNA-PK for the Metabolic Gene Regulation in Response to Insulin
Roger H. F. Wong et al.
CELL (2009)
Pre-mRNA Processing Reaches Back to Transcription and Ahead to Translation
Melissa J. Moore et al.
CELL (2009)
Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer
Chunru Lin et al.
CELL (2009)
PIAS proteins: pleiotropic interactors associated with SUMO
Miia M. Rytinki et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2009)
Proteome analysis of human nuclear insoluble fractions
Hideaki Takata et al.
GENES TO CELLS (2009)
AIRE activated tissue specific genes have histone modifications associated with inactive chromatin
Tonis Org et al.
HUMAN MOLECULAR GENETICS (2009)
Essential Role for DNA-PKcs in DNA Double-Strand Break Repair and Apoptosis in ATM-Deficient Lymphocytes
Elsa Callen et al.
MOLECULAR CELL (2009)
DNA-PK contributes to the phosphorylation of AIRE: Importance in transcriptional activity
Ingrid Liiv et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)
The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression
Tonis Org et al.
EMBO REPORTS (2008)
The cohesin complex and its roles in chromosome biology
Jan-Michael Peters et al.
GENES & DEVELOPMENT (2008)
Evolutionarily conserved and divergent regions of the Autoimmune Regulator (Aire) gene:: a comparative analysis
Mark Saltis et al.
IMMUNOGENETICS (2008)
Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire
Maureen A. Su et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Expression of Aire and the early wave of apoptosis in spermatogenesis
Claudia E. Schaller et al.
JOURNAL OF IMMUNOLOGY (2008)
FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16
Kyu Heo et al.
MOLECULAR CELL (2008)
Functional interaction of AIRE with PIAS1 in transcriptional regulation
Tanja Ilmarinen et al.
MOLECULAR IMMUNOLOGY (2008)
Transcriptional impact of Aire varies with cell type
Mireia Guerau-de-Arellano et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity
Andrew S. Koh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Deletional tolerance mediated by extrathymic Aire-expressing cells
James M. Gardner et al.
SCIENCE (2008)
AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity
Brian J. Ferguson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Transcriptional regulation by AIRE: molecular mechanisms of central tolerance
Paert Peterson et al.
NATURE REVIEWS IMMUNOLOGY (2008)
AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells
Irena Oven et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
The autoimmune regulator directly controls the expression of genes critical for thymic epithelial function
Qing-Guo Ruan et al.
JOURNAL OF IMMUNOLOGY (2007)
Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells
Katharina Aschenbrenner et al.
NATURE IMMUNOLOGY (2007)
HIPK2 - a versatile switchboard regulating the transcription machinery and cell death
Marco A. Calzado et al.
CELL CYCLE (2007)
Daxx cooperates with the Axin/HIPK2/p53 complex to induce cell death
Qinxi Li et al.
CANCER RESEARCH (2007)
Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM and KAP-1 dependent pathway
Yael Ziv et al.
NATURE CELL BIOLOGY (2006)
A topoisomerase IIβ-mediated dsDNA break required for regulated transcription
BG Ju et al.
SCIENCE (2006)
AIRE recruits multiple transcriptional components to specific genomic regions through tethering to nuclear matrix
YX Tao et al.
MOLECULAR IMMUNOLOGY (2006)
The monopartite nuclear localization signal of autoimmune regulator mediates its nuclear import and interaction with multiple importin alpha molecules
T Ilmarinen et al.
FEBS JOURNAL (2006)
The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription
MK Jang et al.
MOLECULAR CELL (2005)
Cooperative activation of transcription by autoimmune regulator AIRE and CBP
J Pitkänen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Chromosomal clustering of genes controlled by the aire transcription factor
JB Johnnidis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Mapping DNA-binding domains of the autoimmune regulator protein
S Purohit et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Subcellular expression of autoimmune regulator is organized in a spatiotemporal manner
H Akiyoshi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
APECED-causing mutations in AIRE reveal the functional domains of the protein
M Halonen et al.
HUMAN MUTATION (2004)
Crystal structure and nuclear magnetic resonance analyses of the SAND domain from glucocorticoid modulatory element binding protein-1 reveals deoxyribonucleic acid and zinc binding regions
P Lo Surdo et al.
MOLECULAR ENDOCRINOLOGY (2003)
Projection of an immunological self shadow within the thymus by the aire protein
MS Anderson et al.
SCIENCE (2002)
Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
C Ramsey et al.
HUMAN MOLECULAR GENETICS (2002)
The autoimmune regulator (AIRE) is a DNA-binding protein
PG Kumar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
J Derbinski et al.
NATURE IMMUNOLOGY (2001)
DNA topoisomerase IIa is required for RNA polymerase II transcription on chromatin templates
N Mondal et al.
NATURE (2001)
The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation
MJ Bottomley et al.
NATURE STRUCTURAL BIOLOGY (2001)
Subcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED)
M Halonen et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2001)
The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein
J Pitkänen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Mutations in the AIRE gene:: Effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy protein
P Björses et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2000)