Associated Risk of Malignancy in Patients with Cardiovascular Disease: Evidence and Possible Mechanism

Cardiovascular disease and malignancy are leading causes of morbidity and mortality. Increased risk of malignancy was identified in patients with cardiovascular disease, including patients with heart failure, heart failure after myocardial infarction, patients undergoing cardiac intervention, and patients after a thrombotic event. Common risk factors and biological pathways can explain this association and are explored in this review. Further research is needed to establish the causes of malignancy in this population and direct possible intervention. (C) 2017 Elsevier Inc. All rights reserved.