期刊
CHEMICAL COMMUNICATIONS
卷 53, 期 55, 页码 7792-7795出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc03035e
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资金
- Ministry of Education, Culture, Sports, Science, and Technology, Japan [26708024, 15K13770, 2401, 15H00739]
- Precursory Research for Embryonic Science and Technology (PRESTO) program from the Japan Science and Technology Agency (JST), Japan
- Tokuyama Science Foundation
- Tokyo Kasei Chemical Promotion Foundation
- Grants-in-Aid for Scientific Research [15K13770, 17K10474, 26708024, 15H00739, 16H01640, 16H01573, 16K15576, 17H04261] Funding Source: KAKEN
Indocyanine green (ICG) derivatives having nucleophilic substituents were synthesized as pH-responsive near-infrared dyes. pH-responsive dyes 1-C with closed-ring structures smoothly internalized and converted to emissive open-ring structures 1-O in response to relatively low pHs in acidic intracellular compartments of HeLa cells.
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