期刊
FOOD & FUNCTION
卷 8, 期 5, 页码 2013-2021出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7fo00297a
关键词
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资金
- Foundation for Science and Technology (FCT, Portugal) [UID/AGR/00690/2013, SFRH/BPD/107855/2015, SFRH/BPD/101413/2014, SFRH/BPD/BPD/68344/2010]
- FEDER [UID/AGR/00690/2013, SFRH/BPD/107855/2015, SFRH/BPD/101413/2014, SFRH/BPD/BPD/68344/2010]
- FEDER, through POCI-COMPETE [POCI-01-0145-FEDER-006984]
- FCT [POCI-01-0145-FEDER-006984]
- Internal Grant Agency of Tomas Bata University in Zlin [IGA/FT/2016/003]
Extracts prepared from leaves, roots, and stems of Solanum stramoniifolium Jacq. (Solanaceae) in 80% ethanol have been tested for their in vitro antioxidant, anti-inflammatory, antimicrobial, and cytotoxic activities with an aim to find new sources of substances for functional foods and food additives. The root extract revealed the highest antioxidant activity in all assays exceeding the trolox capacity, and was the only extract that inhibited nitric oxide production in mouse macrophage cells, showing also the capacity to suppress the growth of all tested human tumor cell lines (MCF-7, NCI-H460, HeLa and HepG2). The leaf extract showed the strongest antimicrobial activity inhibiting all tested clinical isolates. To the author's best knowledge it was the first time that all individual parts of this plant were tested for biological activity together with the phenolic compound characterization.
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