4.7 Article

A membrane-anchored aptamer sensor for probing IFNγ secretion by single cells

期刊

CHEMICAL COMMUNICATIONS
卷 53, 期 57, 页码 8066-8069

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc03576d

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资金

  1. National Key Scientific Program of China [21505039]
  2. Radboudumc PhD grant
  3. Institute of Chemical Immunology [024.002.009]
  4. Netherlands Organization for Scientific Research (NWO) Veni Grant [863.13.024]
  5. NWO Spinoza award
  6. ERC advanced grant PATHFINDER [269019]
  7. KWO of the Dutch Cancer Society [2009-4402]

向作者/读者索取更多资源

Insight into the behavior of individual immune cells, in particular cytokine secretion, will contribute to a more fundamental understanding of the immune system. In this work, we have developed a cell membrane-anchored sensor for the detection of cytokines secreted by single cells using a combination of aptamer-based sensors and droplet microfluidics.

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