期刊
ANALYTICA CHIMICA ACTA
卷 978, 期 -, 页码 48-54出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.aca.2017.04.048
关键词
Indolizine; FRET; Bioimaging; Fluorescent probe; Cu2+
资金
- National Natural Science Foundation of China [21602153]
- Taishan Medical University [2013GCC02]
A new fluorophore indolizine was synthesized and used as a donor to construct FRET system. The chemodosimeter shows a large Stokes shifts (193 nm), high sensitivity, and high selectivity. The probe can quickly (10 min) detect Cu2+ effectively in a wide pH range from 5 to 12 and with a detection limit as low as 9.1 x 10 (9) M. Furthermore, it could be used for imaging Cu2+ in living Glioma cells which demonstrated its value of practical applications in biological systems. (C) 2017 Elsevier B.V. All rights reserved.
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