期刊
ARCHIVES OF MICROBIOLOGY
卷 199, 期 6, 页码 945-952出版社
SPRINGER
DOI: 10.1007/s00203-017-1364-3
关键词
Amino acids; Fusarium graminearum; Mycotoxin production inhibitor; Nitrogen source; Tri gene expression
类别
资金
- Science and Technology Research Promotion Program for Agriculture, Forestry, Fisheries and Food Industry
Fusarium graminearum produces trichothecene mycotoxins under certain nutritional conditions. When L-Thr and its analogue L-allo-threonine were added to brown rice flour solid medium before inoculation, trichothecene production after 4 days of incubation was suppressed. A time-course analysis of gene expression demonstrated that L-Thr suppressed transcription of Tri6, a trichothecene master regulator gene, and a terpene cyclase Tri5 gene. Regulation of trichothecene biosynthesis by altering major primary metabolic processes may open up the possibility to develop safe chemicals for the reduction of mycotoxin contamination might be developed.
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