期刊
THERAPEUTIC DELIVERY
卷 8, 期 9, 页码 753-761出版社
FUTURE SCI LTD
DOI: 10.4155/tde-2017-0059
关键词
bacterial nanocellulose; controlled release; drug delivery; production; storage
资金
- Free State of Thuringia
- European Social Fund [2016 FGR 0045]
Although bacterial nanocellulose (BNC), a natural nanostructured biopolymer network, offers unique material characteristics, the number of drug-loaded BNC-based carriers in clinical trials or on the market is still low. This report provides an overview of aspects still limiting the broad application of BNC as drug-delivery system and the challenges for its future applications. Continuous large-scale production, storability, the loading and controlled release of critical drugs, for example, with high molar mass or highly lipophilic character as well as the formulation of long-term release systems will be highlighted. Recent achievements toward promoting the application of BNC as drug-delivery system and overcoming these obstacles will be discussed. [GRAPHICS] .
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