期刊
BIOMEDICAL OPTICS EXPRESS
卷 9, 期 1, 页码 131-141出版社
OPTICAL SOC AMER
DOI: 10.1364/BOE.9.000131
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资金
- Interdisciplinary Research Project of the University of Texas at Arlington
- National Institutes of Health (NIH) [R03EB022956]
- American Heart Association (AHA) [15BGIA25860045]
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R03EB022956] Funding Source: NIH RePORTER
Noninvasive, direct measurement of local muscle blood flow in humans remains limited. Diffuse correlation spectroscopy (DCS) is an emerging technique to measure regional blood flow at the microvascular level. In order to better understand the strengths and limitations of this novel technique, we performed a validation study by comparing muscle blood flow changes measured with DCS and Doppler ultrasound during exercise. Nine subjects were measured (all males. 27.4 +/- 2.9 years of age) for a rhythmic handgrip exercise at 20% and 50% of individual maximum voluntary contraction (MVC), followed by a post-exercise recovery. The results from DCS and Doppler ultrasound were highly correlated (R = 0.99 +/- 0.02). DCS was more reliable and less susceptible to motion artifact. (C) 2017 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
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