期刊
BIOMEDICAL OPTICS EXPRESS
卷 8, 期 11, 页码 5075-5086出版社
OPTICAL SOC AMER
DOI: 10.1364/BOE.8.005075
关键词
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资金
- National Science Foundation (NSF) [CBET-1643391]
Fluorescence microscopy is an important technique for cellular and microbiological investigations. Translating this technique onto a smartphone can enable particularly powerful applications such as on-site analysis, on-demand monitoring, and point-of-care diagnostics. Current fluorescence smartphone microscope setups require precise illumination and imaging alignment which altogether limit its broad adoption. We report a multi-color fluorescence smartphone microscope with a single contact lens-like add-on lens and slide-launched total-internal-reflection guided illumination for three common tasks in investigative fluorescence microscopy: autofluorescence, fluorescent stains, and immunofluorescence. The open-source, simple and cost-effective design has the potential for do-it-yourself fluorescence smartphone microscopy. (C) 2017 Optical Society of America.
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