期刊
ELECTROCHEMISTRY COMMUNICATIONS
卷 81, 期 -, 页码 5-9出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.elecom.2017.05.018
关键词
Biomolecular recognition; Nanochannel array; Electrochemical detection; Thrombin
资金
- National Natural Science Foundation of China [21575163, 21635004]
- Natural Science Foundation of Jiangsu Province [BK20151437]
A sensitive and label-free method of monitoring the thrombin-aptamer recognition reaction has been developed using an array of nanochannels coupled with an electrochemical detection technique. Due to the highly amplified ion current produced by an array of nanochannels compared to a single nanochannel/pore, a significant increase in detection sensitivity has been achieved.
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