4.6 Article

Label-free monitoring of the thrombin-aptamer recognition reaction using an array of nanochannels coupled with electrochemical detection

期刊

ELECTROCHEMISTRY COMMUNICATIONS
卷 81, 期 -, 页码 5-9

出版社

ELSEVIER SCIENCE INC
DOI: 10.1016/j.elecom.2017.05.018

关键词

Biomolecular recognition; Nanochannel array; Electrochemical detection; Thrombin

资金

  1. National Natural Science Foundation of China [21575163, 21635004]
  2. Natural Science Foundation of Jiangsu Province [BK20151437]

向作者/读者索取更多资源

A sensitive and label-free method of monitoring the thrombin-aptamer recognition reaction has been developed using an array of nanochannels coupled with an electrochemical detection technique. Due to the highly amplified ion current produced by an array of nanochannels compared to a single nanochannel/pore, a significant increase in detection sensitivity has been achieved.

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