期刊
CHEMICAL SOCIETY REVIEWS
卷 46, 期 15, 页码 4709-4773出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cs00492j
关键词
-
资金
- Netherlands Organization of Scientific Research (NWO) [731.015.413]
- BV Cyclotron VU
- Coops foundation
Positron emission tomography (PET) is an important driver for present day healthcare. Fluorine-18 is the most widely used radioisotope for PET imaging and a thorough overview of the available radiochemistry methodology is a prerequisite for selection of a synthetic approach for new fluorine-18 labelled PET tracers. These PET tracers can be synthesised either by late-stage radiofluorination, introducing fluorine-18 in the last step of the synthesis, or by a building block approach (also called modular build-up approach), introducing fluorine-18 in a fast and efficient manner in a building block, which is reacted further in one or multiple reaction steps to form the PET tracer. This review presents a comprehensive overview of the synthesis and application of fluorine-18 labelled building blocks since 2010.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据