Palladium nanoparticles decorated on reduced graphene oxide: An efficient catalyst for ligand- and copper-free Sonogashira reaction at room temperature

This article focuses on a room temperature copper-free Sonagashira cross-coupling reaction in ethanol, catalysed by palladium nanoparticles homogeneously deposited on reduced graphene oxide. The catalyst showed efficient catalytic activity towards the said coupling reaction, and was well characterized using various techniques, and could be reused up to six times with almost constant yield of the desired product. The attractions of this protocol are that the reaction completes within short reaction time under ligand-and copper-free conditions and it avoids harsh reaction conditions.