期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 23, 期 41, 页码 9732-9735出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201701617
关键词
flow techniques; functionalization; gold; nanoparticles; star-shaped
资金
- MIUR-Italy [2015RNWJAM 002]
- Cariplo Foundation Italy, 'Multifunctional gold nanoparticles as a platform for new carbohydratebased vaccines (NANOVAC)'
Star-shaped gold nanoparticles (StarAuNPs) are extremely attractive nanomaterials, characterized by localized surface plasmon resonance which could be potentially employed in a large number of applications. However, the lack of a reliable and reproducible synthetic protocols for the production of StarAuNPs is the major limitation to their spreading. For the first time, here we present a robust protocol to manufacture reproducible StarAuNPs by exploiting a fluidic approach. Star-shaped AuNPs have been synthesized by means of a seed-less protocol, employing ascorbic acid as reducing agent at room temperature. Moreover, the versatility of the bench-top microfluidic protocol has been exploited to afford hydrophilic, hydrophobic and solid-supported engineered StarAuNPs, by avoiding intermediate NP purifications.
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