A near-infrared fluorescence off-on probe for sensitive imaging of hydrogen polysulfides in living cells and mice in vivo

A new hemicyanine-based near-infrared fluorescence off-on probe with phenyl 2-(benzoylthio) benzoate as the recognition moiety to trap hydrogen polysulfides ( H2Sn, n > 1) is developed, and is used for the sensitive imaging of H2Sn in cells and mice in vivo.