期刊
BIOSENSORS & BIOELECTRONICS
卷 94, 期 -, 页码 131-140出版社
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2017.02.032
关键词
Pathogen bacteria; Surface-enhanced Raman scattering; Label method; Label-free method; Multifunctional detection platform
类别
资金
- National Natural Science Foundation of China [21405138, 21505053]
- Science and Technology Planning Project of Guangdong Province, China [2015A030401045, 2016A030310089]
- Ningbo Scientific Innovation Team for Environmental Hazardous Factor Control and Prevention [2016C51001]
- KC. Wong Magna Fund in Ningbo University
Rapid, accurate detection of pathogen bacteria is a highly topical research area for the sake of food safety and public health. Surface-enhanced Raman scattering (SERS) is being considered as a powerful and attractive technique for pathogen bacteria detection, due to its sensitivity, high speed, comparatively low cost, multiplexing ability and portability. This contribution aims to give a comprehensive overview of SERS as a technique for rapid detection of pathogen bacteria based on label and label-free strategies. A brief tutorial on SERS is given first of all. Then we summarize the recent trends and developments of label and label-free based SERS applied to detection of pathogen bacteria, including the relatively complete interpretation of SERS spectra. In addition, multifunctional SERS platforms for pathogen bacteria in matrix are discussed as well. Furthermore, an outlook of the work done and a perspective on the future directions of SERS as a reliable tool for real-time pathogen bacteria detection are given.
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