期刊
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
卷 72, 期 3, 页码 339-347出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00228-015-1993-x
关键词
Adolescents; Asthma; Drug utilization; Pharmacoepidemiology; Questionnaire; Register
资金
- Swedish Research Council
- Swedish Asthma and Allergy Foundation
- European Commission's Seventh Framework 29 Program MeDALL [261357]
- Foundation Masonic Home for Children in Stockholm
- Stockholm County Council
- Swedish Research Council for Health, Working Life and Welfare
- Swedish Initiative for Research on Microdata in the Social And Medical Science (SIMSAM) [340-2013-5867]
Pharmacological treatment is a cornerstone in asthma management, but there is limited evidence on how adolescents use their medication and to what extent their asthma is under control. Therefore, the aim of this study was to compare self-reported and register-based medicine use in asthmatic adolescents. Furthermore, we investigated the association between medicine use, patient characteristics, and degree of asthma control. Cross-sectional analyses of 331 adolescents with asthma from a population-based birth cohort linked to data from the Swedish Prescribed Drug Register. Adolescents' asthma medicine use was assessed with three approaches: self-reported medicine use, self-reported use of someone else's medicines, and dispensed medicines from pharmacies during an 18-month period. Medicine use in adolescents with and without asthma control were compared. In total, 82 % reported use of asthma medicines, 10 % reported use of someone else's medicines, and 62 % were dispensed asthma medicines from pharmacies. Among adolescents with self-reported medicine use, 22 % (n = 60) were neither dispensed medicines nor using someone else's medicines. The majority of those using someone else's medicines had also been dispensed asthma medicine (22 out of 33). Among adolescents with asthma, 176 were fully controlled and 155 were uncontrolled. Also, boys had higher odds of having asthma control than girls. Most adolescents with asthma reported use of asthma medicines, but a considerable proportion were neither dispensed any medicines nor using someone else's medicines. Girls were less likely to achieve asthma control. It is important to combine data sources to understand medicine use among adolescents with asthma.
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