相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Evolutionary Conservation of a GPCR-Independent Mechanism of Trimeric G Protein Activation
Brantley D. Coleman et al.
MOLECULAR BIOLOGY AND EVOLUTION (2016)
Membrane Recruitment of the Non-receptor Protein GIV/Girdin (Gα-interacting, Vesicle-associated Protein/Girdin) Is Sufficient for Activating Heterotrimeric G Protein Signaling
Kshitij Parag-Sharma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Conformational dynamics of a G-protein α subunit is tightly regulated by nucleotide binding
David Goricanec et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Heterotrimeric G proteins as emerging targets for network based therapy in cancer: End of a long futile campaign striking heads of a Hydra
Pradipta Ghosh
AGING-US (2015)
GIV/Girdin Transmits Signals from Multiple Receptors by Triggering Trimeric G Protein Activation
Mikel Garcia-Marcos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Universal allosteric mechanism for Gα activation by GPCRs
Tilman Flock et al.
NATURE (2015)
Probing Gαi1 protein activation at single-amino acid resolution
Dawei Sun et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Therapeutic effects of cell-permeant peptides that activate G proteins downstream of growth factors
Gary S. Ma et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Multimodular biosensors reveal a novel platform for activation of G proteins by growth factor receptors
Krishna K. Midde et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
The guanine nucleotide exchange factor Ric-8A induces domain separation and Ras domain plasticity in Gαi1
Ned Van Eps et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Structural basis for nucleotide exchange in heterotrimeric G proteins
Ron O. Dror et al.
SCIENCE (2015)
Probing Gαi1 protein activation at single-amino acid resolution
Dawei Sun et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling
Nicolas Aznar et al.
ELIFE (2015)
Backbone resonance assignments for G protein αi3 subunit in the GDP-bound state
Yoko Mase et al.
BIOMOLECULAR NMR ASSIGNMENTS (2014)
Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin
Changsheng Lin et al.
MOLECULAR BIOLOGY OF THE CELL (2014)
Energetic analysis of the rhodopsin-G-protein complex links the α5 helix to GDP release
Nathan S. Alexander et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)
GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis
Inmaculada Lopez-Sanchez et al.
NATURE COMMUNICATIONS (2014)
Design, Synthesis, and Functional Evaluation of Leukocyte Function Associated Antigen-1 Antagonists in Early and Late Stages of Cancer Development
Eider San Sebastian et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Ric-8 regulation of heterotrimeric G proteins
Gregory G. Tall
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2013)
(DP2)-P-2: database of disordered protein predictions
Matt E. Oates et al.
NUCLEIC ACIDS RESEARCH (2013)
Backbone resonance assignments for G protein αi3 subunit in the GTP-bound state
Yoko Mase et al.
BIOMOLECULAR NMR ASSIGNMENTS (2012)
Three hotspots important for adenosine A2B receptor activation: a mutational analysis of transmembrane domains 4 and 5 and the second extracellular loop
Miriam C. Peeters et al.
PURINERGIC SIGNALLING (2012)
A Dominant-negative Gα Mutant That Traps a Stable Rhodopsin-Gα-GTP-βγ Complex
Sekar Ramachandran et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
G Protein Binding Sites on Calnuc (Nucleobindin 1) and NUCB2 (Nucleobindin 2) Define a New Class of Gαi-regulatory Motifs
Mikel Garcia-Marcos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
Ka Young Chung et al.
NATURE (2011)
Crystal structure of the β2 adrenergic receptor-Gs protein complex
Soren G. F. Rasmussen et al.
NATURE (2011)
The Nucleotide Exchange Factor Ric-8A Is a Chaperone for the Conformationally Dynamic Nucleotide-Free State of Gαi1
Celestine J. Thomas et al.
PLOS ONE (2011)
Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit
Ned Van Eps et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Structural flexibility of the Gas α-helical domain in the β2-adrenoceptor Gs complex
Gerwin H. Westfield et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Atomic-Level Protein Structure Refinement Using Fragment-Guided Molecular Dynamics Conformation Sampling
Jian Zhang et al.
STRUCTURE (2011)
A Structural Determinant That Renders Gαi Sensitive to Activation by GIV/Girdin Is Required to Promote Cell Migration
Mikel Garcia-Marcos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Enabling IMaC purification of low abundance recombinant proteins from E. coli lysates
Audur Magnusdottir et al.
NATURE METHODS (2009)
GIV is a nonreceptor GEF for Gαi with a unique motif that regulates Akt signaling
Mikel Garcia-Marcos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
GEFs and GAPs: Critical elements in the control of small G proteins
Johannes L. Bos et al.
CELL (2007)
Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins
William M. Oldham et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Solution structure and NMR characterization of the binding to methylated histone tails of the plant homeodomain finger of the tumour suppressor ING4
Alicia Palacios et al.
FEBS LETTERS (2006)
The receptor-bound empty pocket state of the heterotrimeric G-protein α-subunit is conformationally dynamic
Najmoutin G. Abdulaev et al.
BIOCHEMISTRY (2006)
Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins
William M. Oldham et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)
The FoldX web server: an online force field
J Schymkowitz et al.
NUCLEIC ACIDS RESEARCH (2005)
Structure of Gαi1 bound to a GDP-selective peptide provides insight into guanine nucleotide exchange
CA Johnston et al.
STRUCTURE (2005)
Identification and characterization of GIV, a novel Gαi/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles
H Le-Niculescu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Protein production by auto-induction in high-density shaking cultures
FW Studier
PROTEIN EXPRESSION AND PURIFICATION (2005)
Dominant-negative inhibition of pheromone receptor signaling by a single point mutation in the G protein α subunit
YL Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Structural studies on the Ca2+-binding domain of human nucleobindin (calnuc)
E de Alba et al.
BIOCHEMISTRY (2004)
Mammalian Ric-8A (synembryn) is a heterotrimeric Gα protein guanine nucleotide exchange factor
GG Tall et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Soft protein-protein docking in internal coordinates
J Fernández-Recio et al.
PROTEIN SCIENCE (2002)
The SPOT synthesis technique - Synthetic peptide arrays on membrane supports - principles and applications
R Frank
JOURNAL OF IMMUNOLOGICAL METHODS (2002)
Predicting changes in the stability of proteins and protein complexes: A study of more than 1000 mutations
R Guerois et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Structural determinants for GoLoco-induced inhibition of nucleotide release by Gα subunits
RJ Kimple et al.
NATURE (2002)
Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 Å
KC Slep et al.
NATURE (2001)
分享论文
