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S. Chowdhry et al.
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Lynn Bedford et al.
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Alexander Y. Kim et al.
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Dcn1 functions as a scaffold-type E3 ligase for cullin neddylation
Thimo Kurz et al.
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Drug discovery in the ubiquitin-proteasome system
Grzegorz Nalepa et al.
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H Nishitani et al.
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T Kurz et al.
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MD Petroski et al.
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A Hershko
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DT Huang et al.
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SB Cullinan et al.
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Z Nikolovska-Coleska et al.
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A Kobayashi et al.
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