相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism
Pengxu Qian et al.
CELL STEM CELL (2016)
The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs
Kyung H. Choi et al.
BIOCHIMIE (2015)
Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells
Dagmar Walter et al.
NATURE (2015)
Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation
Morgan Jones et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells
Johanna Flach et al.
NATURE (2014)
Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal
Iman Fares et al.
SCIENCE (2014)
Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells
Keiyo Takubo et al.
CELL STEM CELL (2013)
Hematopoietic stem cell expansion: challenges and opportunities
Marta A. Walasek et al.
HEMATOPOIETIC STEM CELLS VIII (2012)
Conditional TRF1 knockout in the hematopoietic compartment leads to bone marrow failure and recapitulates clinical features of dyskeratosis congenita
Fabian Beier et al.
BLOOD (2012)
A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage
Jianwei Wang et al.
CELL (2012)
Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development
Junke Zheng et al.
NATURE (2012)
DNA damage checkpoints in stem cells, ageing and cancer
Tobias Sperka et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
Graeme Hewitt et al.
NATURE COMMUNICATIONS (2012)
A practical guide to evaluating colocalization in biological microscopy
Kenneth W. Dunn et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2011)
Essential roles for Pot1b in HSC self-renewal and survival
Yang Wang et al.
BLOOD (2011)
Prostaglandin E2 Enhances Human Cord Blood Stem Cell Xenotransplants and Shows Long-Term Safety in Preclinical Nonhuman Primate Transplant Models
Wolfram Goessling et al.
CELL STEM CELL (2011)
Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
Toshio Suda et al.
CELL STEM CELL (2011)
Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment
Faiyaz Notta et al.
SCIENCE (2011)
Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells
Anthony E. Boitano et al.
SCIENCE (2010)
Pot1b Deletion and Telomerase Haploinsufficiency in Mice Initiate an ATR- Dependent DNA Damage Response and Elicit Phenotypes Resembling Dyskeratosis Congenita
Hua He et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
How Telomeres Solve the End-Protection Problem
Titia de Lange
SCIENCE (2009)
How Shelterin Protects Mammalian Telomeres
Wilhelm Palm et al.
ANNUAL REVIEW OF GENETICS (2008)
Visualizing spatiotemporal dynamics of multicellular cell-cycle progression
Asako Sakaue-Sawano et al.
CELL (2008)
Engineered telomere degradation models dyskeratosis congenita
Dirk Hockemeyer et al.
GENES & DEVELOPMENT (2008)
TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
Chong Chen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1
Eros Lazzerini Denchi et al.
NATURE (2007)
Telomere protection by mammalian Pot1 requires interaction with Tpp1
Dirk Hockemeyer et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
DNA repair is limiting for haematopoietic stem cells during ageing
Anastasia Nijnik et al.
NATURE (2007)
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
Derrick J. Rossi et al.
NATURE (2007)
Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres
Dirk Hockemeyer et al.
CELL (2006)
Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres
Ling Wu et al.
CELL (2006)
Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells
CC Zhang et al.
NATURE MEDICINE (2006)
Shelterin: the protein complex that shapes and safeguards human telomeres
T de Lange
GENES & DEVELOPMENT (2005)
Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis
D Jo et al.
NATURE MEDICINE (2005)
Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection
M Lei et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
K Ito et al.
NATURE (2004)
Automatic and quantitative measurement of protein-protein colocalization in live cells
SV Costes et al.
BIOPHYSICAL JOURNAL (2004)
DNA damage foci at dysfunctional telomeres
H Takai et al.
CURRENT BIOLOGY (2003)
Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345
KC Jiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
POT1 as a terminal transducer of TRF1 telomere length control
D Loayza et al.
NATURE (2003)
In vitro generation of long-term repopulating hematopoietic stem cells by fibroblast growth factor-1
G de Haan et al.
DEVELOPMENTAL CELL (2003)
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
BM Bolstad et al.
BIOINFORMATICS (2003)
In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein
J Krosl et al.
NATURE MEDICINE (2003)
HOXB4-induced expansion of adult hematopoietic stem cells ex vivo
J Antonchuk et al.
CELL (2002)
In vitro self-renewal division of hematopoietic stem cells
H Ema et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
分享论文
