期刊
CURRENT ONCOLOGY REPORTS
卷 19, 期 5, 页码 -出版社
SPRINGER
DOI: 10.1007/s11912-017-0590-9
关键词
Esophageal neoplasms/TH; Immunotherapy
类别
Esophageal squamous cell carcinoma have been frustrating to treat, with slow progress made on extending survival. Immunotherapy targeting immune checkpoints, T cells, and infiltrating lymphocytes has shown promise in early studies. The efficacy of pembrolizumab and nivolumab is encouraging. Anti-chemokine receptors and oncolytic viruses are also making headway against these stubborn tumors; improved results when immune checkpoint inhibitors are combined with radiation therapy are eagerly anticipated. Adoptive T cell therapy and vaccines are also under development. The importance of a multidisciplinary approach cannot be emphasized enough.
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