期刊
MOLECULAR & CELLULAR ONCOLOGY
卷 4, 期 2, 页码 -出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/23723556.2016.1264351
关键词
Autophagy receptor; cancer; endoplasmic reticulum; ER-phagy; LIR; oncogene; recovER-phagy; SEC62; selective autophagy; TLOC1; tumor
类别
Amplification of the candidate oncogene TLOC1/SEC62 in tumors correlates with reduced patient survival. The recently reported role of SEC62 as an autophagy receptor that controls endoplasmic reticulum (ER) size and function might open new scenarios for understanding the phenotypes and treat SEC62high tumors, which are characterized by high ER stress tolerance.
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