期刊
JOURNAL OF FUNCTIONAL FOODS
卷 38, 期 -, 页码 355-362出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jff.2017.09.050
关键词
Catathelasma ventricosum; Carboxymethylation; Directional modification; Structure characterization; Antioxidant activity; Antibacterial activity
资金
- China Postdoctoral Science Foundation [2015M580795]
- Fund Project of Sichuan Provincial Department of Education [16ZB0053]
- Scientific Research Foundation of Sichuan Agricultural University [06021400]
The mycelial polysaccharides from Catathelasma ventricosum (mCVP-1Ss) were modified by carboxymethylation with different reaction conditions (reaction time, temperature and chloroacetic acid dosage) to obtain carboxymethylated mCVP-1Ss (cmCVP-1Ss), and their primary structures were characterized. NMR results indicated that substitution of carboxylate groups appeared primarily at C-6 position. Carboxymethylation significantly improved the antioxidant and antibacterial activities of mCVP-1S, while cmCVP-1Ss with medium degree of substitution (DS) and stable triple-helical structurepossessed the greatest DPPH radical scavenging activity, reducing power, metal chelating activity andantibacterial activity. When the concentration of cmCVP-1S(3/8/13) reached 7.5 mg/mL, it showed excellent inhibitory effect on Escherichia coli, Salmonella Typhimurium, Staphylococcus aureus and Bacillus subtilis. However, excessive DS might destroy the triple helical structure of cmCVP-1S, thus significantly weaken the biological activities of cmCVP-1S.cmCVP-1Ss possess excellent antioxidant and antibacterial activities and have potential to be used as new types of antioxidant and antibiotic, which are inartificial and safer. (C) 2017 Elsevier Ltd. All rights reserved.
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