期刊
JOURNAL OF FUNCTIONAL FOODS
卷 30, 期 -, 页码 97-107出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jff.2017.01.015
关键词
Lycium ruthenicum; Anthocyanin; Antioxidant property; PC12 cell; Cytoprotective effect
资金
- National Natural Science Foundation of China [31171666]
- Pilot project by Ningxia Academy of Agriculture and Forestry Science [NKYJ-15-16, NKYZ-16-05]
- Innovation and entrepreneurship training program for Jiangsu students [201610307016X]
The fruit of Lycium ruthenicum Murray has been widely used as a precious Chinese herbal medicine. In this study, the major anthocyanin in L ruthenicum fruit was obtained via an AKTA purifier system with YMC-Pack ODS-A column and identified by mass and nuclear magnetic resonance spectroscopy to be petunidin 3-0-[6-0-(4-0-(trans-p-coumaroyl)-alpha-L-rhamnopyranosyl)-beta-D-glucopyranoside]-5-0-[beta-D-glucopyranoside] (compound 1). Compound 1 exhibited higher scavenging activities against 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid), 1,1-dipheny1-2-picrylhydra-zyl and superoxide radicals than the crude extract of anthocyanins. Moreover, compound 1 was demonstrated to have potential cyto-protective effect on hydrogen peroxide-induced intracellular reactive oxygen damage in neuronlike rat pheochromocytoma line cells by promoting cell proliferation, mitigating lipid peroxidation and regulating endogenous antioxidant enzymes (glutathione peroxidase, superoxide dismutase and catalase). (C) 2017 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据