期刊
AQUACULTURE
卷 479, 期 -, 页码 538-543出版社
ELSEVIER
DOI: 10.1016/j.aquaculture.2017.06.036
关键词
Danofloxacin; Residues; European sea bass; Withdrawal period
资金
- Greek General Secretariat for Research and Technology, Ministry of Education, Life Long Learning and Religious Affairs
- Program: FISHANTIMICROBIALS [11SYN_3_1929]
Residue depletion of danofloxacin was investigated in European sea bass after a multiple (5 days) in-feed administration of danofloxacin mesylate (10 mg/kg bw per day) under experimental field conditions at water temperature of 16 degrees C and 27 degrees C. Ten fish per sampling point were examined during and after treatment. Samples of muscle plus skin in natural proportions were analyzed for danofloxacin determination by Ultra-Performance Liquid Chromatography equipped with an Ultraviolet Photodiode Array Detector (UPLC-PDA). Danofloxacin concentrations in muscle tissues increased during medication period and then decreased rapidly. The elimination half-lives were estimated to be t(1/2) = 16.87 h and 21.13 h at 27 degrees C and 16 degrees C, respectively. Withdrawal periods (Wt) were calculated after medication using the WT1.4 program and were found to be at 95% tolerance limit, 7 and 4 days at 16 degrees C and 27 degrees C, respectively.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据