期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 23, 期 50, 页码 12096-12099出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201701979
关键词
amination; benzoxazinone; electrochemistry; nitrogen heterocycles; sustainable chemistry
资金
- Advanced Lab for Electrochemistry and Electrosynthesis-ELYSION (Carl Zeiss Stiftung)
- Grants-in-Aid for Scientific Research [26220804] Funding Source: KAKEN
1,4-Benzoxazin-3-ones are important structural motifs in natural products and bioactive compounds. Usually, the synthesis of benzoxazinones requires transition-metal catalysts and pre-functionalized substrates such as aryl halides. However, the anodic C-H amination of phenoxy acetates offers a very efficient and sustainable access to these heterocycles. The presented electrochemical protocol can be applied to a broad scope of alkylated substrates. Even tert-butyl moieties or halogen substituents are compatible with this versatile method.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据