4.2 Article

Cu(NO3)(2)-catalysed direct synthesis of 5-substituted 1H-tetrazoles from alcohols or aldehydes

期刊

JOURNAL OF CHEMICAL RESEARCH
卷 -, 期 1, 页码 25-29

出版社

SAGE PUBLICATIONS LTD
DOI: 10.3184/174751917X14815427219248

关键词

copper-catalysed; 5-substituted 1H-tetrazole; alcohol; aldehyde

资金

  1. National Natural Science Foundation of China [21402062]
  2. Natural Science Foundation of Jiangsu Province [BK20130404, BK20141246]
  3. Scientific and Technological Research Project of Lianyungang [CG1303, CN1401]
  4. Priority Academic Program Development of Jiangsu Higher Education Institutions
  5. Open-end Funds of Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening [2015HYB11]

向作者/读者索取更多资源

A simple, convenient and practical protocol to synthesise 5-substituted 1H-tetrazoles from alcohols or aldehydes is reported. Using ammonia and sodium azide as nitrogen sources and Cu(NO3)(2) as catalyst, benzylic alcohols and benzaldehydes were directly converted into 5-substituted 1H-tetrazoles in a one-pot procedure.

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