期刊
CHEMICAL SCIENCE
卷 8, 期 1, 页码 40-62出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6sc02118b
关键词
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资金
- Pfizer Worldwide Medicinal Chemistry
Suzuki-Miyaura cross-coupling reactions of heteroaryl polyhalides with aryl boronates are surveyed. Drawing on data from literature sources as well as bespoke searches of Pfizer's global chemistry RKB and CAS Scifinder (R) databases, the factors that determine the site-selectivity of these reactions are discussed with a view to rationalising the trends found.
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