期刊
CHEMISTRY & BIODIVERSITY
卷 14, 期 8, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.201700092
关键词
Pulicaria incisa; Asteriscus graveolens; Aerials parts; Essential oils; GC; GC; MS; Antimicrobial Activity
资金
- Abou Bekr BELKAID University - Tlemcen and the Ministry of Higher Education and Scientific Research of the Algerian People's Democratic Republic under the project CNEPRU [E02020130152/2014-2018]
In recent years, antimicrobial activities of essential oils have been intensively explored, mainly in researching and developing new antimicrobial agents to overcome microbial resistance. The present study investigates the chemical composition and antimicrobial activities of essential oils obtained from two Asteraceae: Asteriscus graveolens (Forssk.) Less. and Pulicaria incisa (Lam.) DC. Chemical analysis was performed using a combination of capillary GC-FID and GC/MS analytical techniques. The major component of Asteriscus graveolens were cis-chrysanthenyl acetate (31.1%), myrtenyl acetate (15.1%), and kessane (11.5%), while for Pulicaria incisa the main components were chrysanthenone (45.3%) and 2,6-dimethylphenol (12.6%). The oils obtained from the aerial parts were tested against sixteen microbial strains by agar well diffusion technique and dilution methods and showed minimum inhibitory concentrations (MIC) in the range of 19 - 1250 g/ml. A good antibacterial activity against a common nosocomial pathogen, Acinetobacter baumanniiATCC 19606 was observed, especially from Pulicaria incisa essential oil, with a MIC value up to 19 g/ml. These results give significant information about the pharmacological activity of these essential oils, which suggest their benefits to human health, having the potential to be used for medical purposes.
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