期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 56, 期 39, 页码 11807-11811出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201705916
关键词
amination; DFT calculations; nitrogen heterocycles; nucleophilic aromatic substitution; sodium hydride
资金
- Nanyang Technological University (NTU)
- Singapore Ministry of Education (Academic Research Fund Tier 1) [RG2/15]
- Tokyo Biochemical Research Foundation
- Tohoku University
- Tohoku Kaihatsu Memorial Foundation
- Grants-in-Aid for Scientific Research [17J10805, 17H06173] Funding Source: KAKEN
A method for the nucleophilic amination of methoxy arenes was established by using sodium hydride (NaH) in the presence of lithium iodide (LiI). This method offers an efficient route to benzannulated nitrogen heterocycles. Mechanistic studies showed that the reaction proceeds through an unusual concerted nucleophilic aromatic substitution.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据
分享论文
