4.6 Review

Nuclear Import of Hepatitis B Virus Capsids and Genome

期刊

VIRUSES-BASEL
卷 9, 期 1, 页码 -

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MDPI AG
DOI: 10.3390/v9010021

关键词

nuclear transport; genome release; hepatitis B virus; nuclear pore; nucleoporin

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资金

  1. Fondation pour la recherche medicale (FRM) [FRM 2011 DEQ20110421299]
  2. National French Agency for Research (ANRS) [AAP 2014-2]

向作者/读者索取更多资源

Hepatitis B virus (HBV) is an enveloped pararetrovirus with a DNA genome, which is found in an up to 36 nm-measuring capsid. Replication of the genome occurs via an RNA intermediate, which is synthesized in the nucleus. The virus must have thus ways of transporting its DNA genome into this compartment. This review summarizes the data on hepatitis B virus genome transport and correlates the finding to those from other viruses.

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