期刊
VIRUSES-BASEL
卷 9, 期 1, 页码 -出版社
MDPI AG
DOI: 10.3390/v9010021
关键词
nuclear transport; genome release; hepatitis B virus; nuclear pore; nucleoporin
类别
资金
- Fondation pour la recherche medicale (FRM) [FRM 2011 DEQ20110421299]
- National French Agency for Research (ANRS) [AAP 2014-2]
Hepatitis B virus (HBV) is an enveloped pararetrovirus with a DNA genome, which is found in an up to 36 nm-measuring capsid. Replication of the genome occurs via an RNA intermediate, which is synthesized in the nucleus. The virus must have thus ways of transporting its DNA genome into this compartment. This review summarizes the data on hepatitis B virus genome transport and correlates the finding to those from other viruses.
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