期刊
VIRUSES-BASEL
卷 9, 期 4, 页码 -出版社
MDPI AG
DOI: 10.3390/v9040088
关键词
chloroviruses; giant viruses; hyaluronan synthesis; chitin synthesis; nucleotide sugar synthesis; glycan synthesis; glycan structures; glycoproteins
类别
资金
- NIH
- NSF
- DOE
- Stanley Medical Research Institute
Chloroviruses are large double-stranded DNA (dsDNA) viruses that infect certain isolates of chlorella-like green algae. They contain up to approximately 400 protein-encoding genes and 16 transfer RNA (tRNA) genes. This review summarizes the unexpected finding that many of the chlorovirus genes encode proteins involved in manipulating carbohydrates. These include enzymes involved in making extracellular polysaccharides, such as hyaluronan and chitin, enzymes that make nucleotide sugars, such as GDP-L-fucose and GDP-D-rhamnose and enzymes involved in the synthesis of glycans attached to the virus major capsid proteins. This latter process differs from that of all other glycoprotein containing viruses that traditionally use the host endoplasmic reticulum and Golgi machinery to synthesize and transfer the glycans.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据