期刊
TRANSCRIPTION-AUSTIN
卷 8, 期 1, 页码 26-31出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/21541264.2016.1246076
关键词
epigenetics; exosome; H3K36me; HDAC; heterochromatin; Set2
资金
- Japan Society for the Promotion of Science (JSPS) [25250022]
- JSPS [26440001]
- Ministry of Education, Culture, Sports, Science, and Technology of Japan [15H01339]
- Grants-in-Aid for Scientific Research [16K14638, 26440001, 25250022, 15H01339] Funding Source: KAKEN
Epigenetic marks determine cell fate via numerous reader proteins. H3K36 methylation is a common epigenetic mark that is thought to be associated with the activities of the RNA polymerase 2 C-terminal domain. We discuss a novel silencing mechanism regulated by Set2-dependent H3K36 methylation that involves exosome-dependent RNA processing.
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