期刊
CURRENT PSYCHIATRY REVIEWS
卷 13, 期 2, 页码 102-110出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1573400513666170502125017
关键词
Theory of mind; adolescence; neuroimaging; social cognition; unaffected relatives; high risk; endophenotype; mentalising
类别
资金
- US-UK Fulbright Commission
- English-Speaking Union
- National Science Fund China [31400884, 81088001, 91132701]
- Beijing Training Project for the Leading Talents in S T [Z151100000315020]
Theory of mind deficit is a core feature of schizophrenia and is considered a vulnerability marker of the disorder. The majority of studies measuring theory of mind in schizophrenia involve multiple-episode or chronic schizophrenia patients, and therefore it is important to delineate whether these deficits occur before or following illness-onset by assessing high-risk subjects (clinical high risk and ultra-high risk), early-onset psychosis, and first-degree relatives. We address the question of whether theory of mind impairment is specific or a facet of general cognitive impairment in these clinical populations, and incorporate genetic and neuroimaging studies on the theory of mind. The review provides a succinct evaluation of the literature, discusses current limitations and proposes future directions.
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